2025/2/10
【演講公告】2/26 荷蘭University of Amsterdam的Birte U. Forstmann教授和Leiden University的 Steven Miletić教授為大家帶來精彩演講
本系於2/26 週三邀請來自荷蘭University of Amsterdam的Birte U. Forstmann教授和Leiden University的 Steven Miletić教授為大家帶來一場演講包含兩個講題和個別的Q& A時間,敬請踴躍出席。
講題一:
Joint Modeling of the Deep Brain’s Form and Function
講者:Birte U. Forstmann教授
時間:2025-2-26(三)13:10-14:00含Q&A
地點:成大社會科學院北棟2樓心理學系階梯教室
演講語言:英文
演講摘要:
The subcortex has paramount importance for cognitive processes and is affected early in practically all neurodegenerative diseases. Yet, in the past decades, the human neurosciences have been dominated by a cortico-centric viewpoint, while the human subcortex, the Deep Brain, has remained relatively uncharted territory. It is notoriously more difficult to study with non-invasive structural and functional MRI. Its nuclei are small, numerous, and heterogeneous in (micro)structure and function, they lie deep in hard-to-image brain regions, and most of them have been poorly characterized even with quantitative ultra-high field MRI. According to the Federative Community on Anatomical Terminology (FCAT, 1998), there are approximately 455 subcortical structures; only a fraction of these are depicted in available standard MRI-atlases (Forstmann et al., 2017). My research aims to pivot the prevalent cortico-centric viewpoint to a whole-brain perspective on brain and cognition in health and disease. In this talk, I will present an overview of past, present, and potential future advances that enable us to start charting the terra incognita of the deep brain. To this end, I will show how multi-modal post-mortem data can be used to augment multi-modal in-vivo data in the atlasing and characterizing of small subcortical nuclei. I will introduce a novel Bayesian joint modeling of brain and behavior that explores the functional role of cortico-subcortical loops in adaptive decision making. Finally, I will explain how the combination of these methodologies will advance a powerful vision of a truly whole-brain conceptual understanding of cognition in the living human brain.
講題二:
Explaining multi-scale choice dynamics
講者:Steven Miletić教授
時間:2025-2-26(三)14:10-15:00含Q&A
地點:成大社會科學院北棟2樓心理學系階梯教室
演講語言:英文
演講摘要:
Decision making is often studied in highly controlled experimental paradigms where the environment is mostly stationary. This contrasts with the dynamic and non-stationary environments in which humans evolved, which necessitates continuous adaptation of behavior. My work proposes that adaptive mechanisms cause systematic fluctuations in choice performance across trials, both in non-stationary and in stationary choice environments. In this talk, I will present a set of experiments and formal models of choice behavior that integrate adaptive mechanisms. Through these, I will demonstrate that incorporating adaptive mechanisms in evidence-accumulation models is a promising way forward to understanding not only how choice behavior changes across time, but also why it changes.
講題一:
Joint Modeling of the Deep Brain’s Form and Function
講者:Birte U. Forstmann教授
時間:2025-2-26(三)13:10-14:00含Q&A
地點:成大社會科學院北棟2樓心理學系階梯教室
演講語言:英文
演講摘要:
The subcortex has paramount importance for cognitive processes and is affected early in practically all neurodegenerative diseases. Yet, in the past decades, the human neurosciences have been dominated by a cortico-centric viewpoint, while the human subcortex, the Deep Brain, has remained relatively uncharted territory. It is notoriously more difficult to study with non-invasive structural and functional MRI. Its nuclei are small, numerous, and heterogeneous in (micro)structure and function, they lie deep in hard-to-image brain regions, and most of them have been poorly characterized even with quantitative ultra-high field MRI. According to the Federative Community on Anatomical Terminology (FCAT, 1998), there are approximately 455 subcortical structures; only a fraction of these are depicted in available standard MRI-atlases (Forstmann et al., 2017). My research aims to pivot the prevalent cortico-centric viewpoint to a whole-brain perspective on brain and cognition in health and disease. In this talk, I will present an overview of past, present, and potential future advances that enable us to start charting the terra incognita of the deep brain. To this end, I will show how multi-modal post-mortem data can be used to augment multi-modal in-vivo data in the atlasing and characterizing of small subcortical nuclei. I will introduce a novel Bayesian joint modeling of brain and behavior that explores the functional role of cortico-subcortical loops in adaptive decision making. Finally, I will explain how the combination of these methodologies will advance a powerful vision of a truly whole-brain conceptual understanding of cognition in the living human brain.
講題二:
Explaining multi-scale choice dynamics
講者:Steven Miletić教授
時間:2025-2-26(三)14:10-15:00含Q&A
地點:成大社會科學院北棟2樓心理學系階梯教室
演講語言:英文
演講摘要:
Decision making is often studied in highly controlled experimental paradigms where the environment is mostly stationary. This contrasts with the dynamic and non-stationary environments in which humans evolved, which necessitates continuous adaptation of behavior. My work proposes that adaptive mechanisms cause systematic fluctuations in choice performance across trials, both in non-stationary and in stationary choice environments. In this talk, I will present a set of experiments and formal models of choice behavior that integrate adaptive mechanisms. Through these, I will demonstrate that incorporating adaptive mechanisms in evidence-accumulation models is a promising way forward to understanding not only how choice behavior changes across time, but also why it changes.